Basic Information
VIS ID
TVIS10020362
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1057
End
2107
Orient
-
Integrated sequence
CTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTG
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
167210932/166289780 (Hg38)
End
167211982/166290830 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/903443; hsa-mir-1305/Downstream/4895354;
Nearest TSS
ENST00000502981/Upstream/414822; ENST00000503003/Downstream/235289;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/415591, chr4-CpG: 27/Downstream/2027568
Upstream sequence
TGTAAGAAAAAATGAAAGAAATAGTTCCCTGCCTTTGGGAAATAGACTGACAGCAGTGGCAGACCTTTGAGGTTTATTACATTCTTTGTTTTAGTAGTGC
Downstream sequence
caaccaaaattgcaatagagctctagttgataaaTATTAATACAGTGGACAATCTAGAATATACTAACTTGCTTTCTTTAAGAGATAAGAGATATATaca
Target sequence
gaatgggatcttggattgaaagcttcaaatgcctagggtgacttgaacacctgagggctggagttatctggatactttttactcacatgtctggtgcctgggatggtaagacttgaactcgttgatcagattgtcttctcattgcctctccatatagaccgggcttcctcaaacatgacaatctctgggttactggactttttgcatagaggttcggggtccatgaatgaatatttcagtgaacgaggtctttac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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