VISDB Viral Integration Site DataBase

VIS ID

TVIS10020363

Fusion event

HBV-AGO1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1181

End

2281

Orient

+

Integrated sequence

GTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTC

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36340120/35874519 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-503-5p ; hsa-mir-148b-3p ; hsa-mir-130b-3p ; hsa-mir-106b-5p ; hsa-mir-107 ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-320c ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-151a-5p ; hsa-mir-93-3p ; hsa-mir-769-3p ; hsa-mir-421 ; hsa-mir-652-3p ; hsa-mir-628-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-146b-5p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-5p ; hsa-mir-326 ; hsa-mir-328-3p ; hsa-mir-330-3p ; hsa-mir-378a-3p ; hsa-mir-320a ; hsa-mir-195-5p ; hsa-mir-194-5p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-138-5p ; hsa-let-7g-5p ; hsa-mir-212-3p ; hsa-mir-34a-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-197-3p ; hsa-mir-106a-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-31-5p ; hsa-mir-29a-3p ; hsa-mir-26a-5p ; hsa-mir-25-3p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-let-7e-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3678-3p ; hsa-mir-4779 ; hsa-mir-2467-3p ; hsa-mir-19a-3p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-103a-3p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7i-5p ; hsa-mir-1-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-4684-5p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-942-5p ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-325 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-4632-5p ; hsa-mir-6735-5p ; hsa-mir-4436b-3p ; hsa-mir-100-3p ; hsa-mir-3166 ; hsa-mir-4756-3p ; hsa-mir-1324 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-8075 ; hsa-mir-219a-2-3p ; hsa-mir-218-5p ; hsa-mir-4266 ; hsa-mir-4717-5p ; hsa-mir-3919 ; hsa-mir-4695-5p ; hsa-mir-6510-5p ; hsa-mir-4690-5p ; hsa-mir-6165 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4279 ; hsa-mir-4777-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-892b ; hsa-mir-4514 ; hsa-mir-4524b-3p ; hsa-mir-4692

Nearest miRNA

hsa-mir-12136/Upstream/1203775; hsa-mir-101-1/Downstream/1287044;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/64609, chr1-CpG: 29/Downstream/8381

Upstream sequence

ttatccaaaatcttgtaggacacgttcaaaattgtagacttactccaagagcaatatggagagttttaagcagtgatatgaccAAAGTTCTTAATTCATG

Downstream sequence

tctctccctctccttgggcctccctattccttgagacacaacaatactgaaagtaggccaattaataaccctgcaatggcctgtaagtgttcaagtgaaa

Target sequence

GTGATAGTCCCTCAGTTGTTTTGTTTCATACCAACTCTTGGTTTCATAGCTATAAGCTTTTTACAATAAAGGCAAATTTCCTCTTTCAGTTTCTTGTTGCTCCCTCTGGTCTGTTGAGAGCACTGTGATATAACTTAGGGGTATGACCAATCAGTCTTCCTGATTTTTCAGTCTGTCTTGACAGTTCTCTCAAAAGCCTCTCTTTTCCCGATCAGCTTCACCTCTTCTCTCGTGAAAGAGTACTTTTCCTAGATC