Basic Information
VIS ID
TVIS10020364
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2276
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
72744473/71878756 (Hg38)
End
72745523/71879806 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/5601828; hsa-mir-1243/Downstream/4693762;
Nearest TSS
ENST00000502981/Upstream/54776; ENST00000344413/Downstream/151998;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/691004, chr4-CpG: 30/Downstream/152041
Upstream sequence
ttttagtagagacagcatttcactgtgttagccaggatgatctcgatctcctgacctcgtgatccgcccgcctcggcctcccaaagtgctgggattacag
Downstream sequence
Gcttcaggaggccgaggcgggcagatcaggaggtcaggagatcgagaccgtcctggttaacacggtgaaacccggtctctactaaaaatacaaaaaatta
Target sequence
ATTCAGAGATTTTTGTTTCCAGTATATTTTGATTTTTGATCATCTCAATTCAGCTCATAAAATTAAAGTGAAGCCATAACAAAAATGACCAATTTGTTGGCAATTTTATAGGTATTTGGAATTTTGAGATATAGTCTGTGGCTGTATTGAATGTGAATACCAAGTGATTTACTATATCTCTTGAACTATTTGAGGGTAATAATATAAATGAAGATATCTTTCTTTAGAACTACCAAAAAATACCTTTGTATCTAT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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