Basic Information
VIS ID
TVIS10020370
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1165
End
2265
Orient
+
Integrated sequence
CAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCT
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
59841737/59447956 (Hg38)
End
59842787/59449006 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1228/Upstream/1623264; hsa-let-7i/Downstream/2811353;
Nearest TSS
ENST00000382841/Upstream/36785; ENST00000549465/Downstream/75178;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/527285, chr12-CpG: 76/Downstream/146864
Nearby gene
RNU6-871P(+2717) ;
Upstream sequence
CCAATAGGAATGCTCCGTCCAGAATGGTGGCTACAATGCCCAATAGGAGAGATTCATACTGAATGACATCAAACTGGCCCAATAGGAAGGGTTTATATTG
Downstream sequence
aattttatataatgaaatcatacagtatgtatcctactgtgttggcttctttcccttaaccttatgcttTCTggccaggcgcagtggcttacgcctgtaa
Target sequence
AGCTAAACTTTCTCCTTCTCAGTCTCCtgctagttattctacatttgatcctctccatctctacatgatttctctgccttttgctgccctgctgtaagttccagaagtctagcctcttcaagctacatcactcagacactcgggccctctggttttcagtgggatttagacaatggcagtaactggaagaaatcagagtatgggaggcaaaagagatcaggctatttatttctccatccctatacttttcctgct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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