VISDB Viral Integration Site DataBase

VIS ID

TVIS10020371

Fusion event

HBV-NUP37 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1165

End

2265

Orient

+

Integrated sequence

CAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCT

Chromosome

chr12

Cytoband

q23.2

Reference genome

Start

End

102481679/102087901 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-10a-5p ; hsa-mir-3915 ; hsa-mir-3928-3p ; hsa-mir-1200 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6832-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-3161 ; hsa-mir-580-3p ; hsa-mir-4753-3p ; hsa-mir-670-5p ; hsa-mir-4669 ; hsa-mir-3657 ; hsa-mir-4251 ; hsa-mir-130b-5p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-3919 ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-3925-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-548c-3p ; hsa-mir-5582-3p ; hsa-mir-4773

Nearest miRNA

hsa-let-7i/Upstream/1896902; hsa-mir-1178/Downstream/1842524;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/24646, chr12-CpG: 28/Downstream/31989

Upstream sequence

CTTTCTTTTGTGAACAGTTCAATACATGTACTGAACATTTGGTATAGAGAACACTGAGAaacattttttgggtgtttactgattctgggaattacatgta

Downstream sequence

GTATTCCTGTCCAATGAACCAAAGTTTTACCTAATTTTTAACCAGTATTTTATCCTGAACAGAACCTGACATTTAAGAAAACTAACAAACAAACAAAAAC

Target sequence

gacagaaggattgcttgagcccaggagttcaagaccagcctggcaaatacagtgaaacttcgtctctacaaaacacataaaaattggccaggcatagtgatgcacacttgtagccccagctattacttgggaggctaaaatggcaggctgacgtgggaggattgcttgagcacaggaggtggaggctacaatgtgccacgtttgcacctctgcactccagcctgggtgacagagaccctgtctcaaaacaacaac