VISDB Viral Integration Site DataBase

VIS ID

TVIS10020373

Fusion event

HBV-SLCO1B1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1165

End

2265

Orient

+

Integrated sequence

CAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCT

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

21380328/21227394 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-511-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/3552950; hsa-let-7i/Downstream/2985027;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/673274, chr12-CpG: 34/Downstream/210141

Upstream sequence

CTTGCTTATTTAAGCCTAGTTAAAGCAAGCTGACCACCCACATGGCCAATAGACTCAGACACTTCTGGACCATTTACAGGCATTGTCCTGAGCTCCCTTG

Downstream sequence

GTTCAGGATACATCTCTGGAGTAAAGACCTAGGATCAAATTTACCAAACAGACTCTCTTCCATTTAATGTGTAAATTCACTATCTAAAATCCCCAGCAGA

Target sequence

cggaggttgcagtaagccaagctcatggcactgctctccggcctggctgacagagcgagactctgtctcaaaaaaagaaaaaaaaagaacattaaaaaaaattaaagaagcttctgactgtattattctaactgtatgaccttttgtaaaagggccaaactatgaagacaatgaaacatcagtggttgctaggagctcagtggggagaagataaggatgagtaggtggagcacagggcattttaagggtggtgaa