Basic Information
VIS ID
TVIS10020374
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1076
End
2176
Orient
+
Integrated sequence
ATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAAC
Host Sequence
Chromosome
chr19
Cytoband
q13.41
Reference genome
GRCh37/hg19
Start
52098104/51594851 (Hg38)
End
52099154/51595901 (Hg38)
Orient
+
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/387842; hsa-let-7e/Downstream/96711;
Nearest TSS
ENST00000633603/Upstream/13483; ENST00000601315/Downstream/3388;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/104, chr19-CpG: 20/Downstream/2647
Nearby gene
LINC01530(-471) ; LOC339352(+3659) ;
Upstream sequence
gtgctgggattatgggtgtgagctactacacccagccatggctgtatatacatttttatgttaatttctggatttggagttttagaactattggactgtg
Downstream sequence
cactcagtgggtatttgttaaatgaatgaatGAAAGtttgagctgagacttgaaggtaagagttaggtctaccacagtgtttagggaagtgtcttgcgca
Target sequence
GCCCAGCCTGACACCTTCTCACTCTCGCCCTTCAACCTGGGTGCAGTGCGAGTGCACCCTCCTCTGTCCTGGTTACAACACAGAGTGGTCAGGGCTGGCCCAGGGGGTGCTcaggaggctgtgggaacacagaggaggtgctagacccagcccagggttcaggaaagaccttacagagcaaaggacctcaaatctaccacatccaaacgaaatcccagattccctgtcctaaacctgctcctctcacaatctttc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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