Basic Information
VIS ID
TVIS10020377
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
902
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
93243814/92231586 (Hg38)
End
93244862/92232634 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12123/Upstream/1026027; hsa-mir-10400/Downstream/797117;
Nearest TSS
ENST00000518652/Upstream/128300; ENST00000522531/Downstream/181011;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/87174, chr8-CpG: 56/Downstream/732931
Upstream sequence
tgacccagcatatagttacttgtttatttgtttgttgacagtctgacacccccaacccctcatgaaccccaggaatgcagagacttctgttaattttatt
Downstream sequence
ACACTAGAAATAAGATGCTTCCTGAAACTTTCTTTTTTTGCAAACACTGCTCTTTTACACTCtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtTTTAA
Target sequence
gcactctgtgtctagcttgaggtttgtgaacacaccaatcagcaccctgtgtctagctcaaggtttgtgaatgcaccaatcagtgctctgtgtctagctaatctagtggggacttggagaacttttgtgtttagctcagggattgtaaacgcaccaatcagcaccctgtcaaaatgggccaatcagctctctgtaagaccaatcagcttgctgtaaaatggaccaatcagcaggatgtgggtggggccagataag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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