Basic Information
VIS ID
TVIS10020383
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
898
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr7
Cytoband
q31.32
Reference genome
GRCh37/hg19
Start
121062584/121422530 (Hg38)
End
121063632/121423578 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10525/Upstream/4402211; hsa-mir-10399/Downstream/5634510;
Nearest TSS
ENST00000635602/Upstream/26166; ENST00000471837/Downstream/226782;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/25914, chr7-CpG: 72/Downstream/449414
Upstream sequence
tattattttatccttaagtaatttcaAATGGGATAAAGGAAAGAAACTGTACTAAGGAGTACATTcaactctgtagccacaaattaaaaaatttgaattt
Downstream sequence
taatcccagcactttgggaggccgaggcgggcggatcacgaggtcaggagctcaagatcatcctgaaaccccggtgaaaccccgtctctactaaaaatac
Target sequence
gagaacttctgtgtctacactctgtatctagctaatctagtggggaggtggagaacctttgtgtctagctcagggattgtaaatgcaccaatcagaccactcggctctctgtaaaatggaccaatcagcaggatgtgggtggggccagataagagaataaaagcaggctgcccgagccagcagtggcaacctgctccggtccccttccacactgtggaagctttgttctttcgctctttgcaataaatcttgctg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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