Basic Information
VIS ID
TVIS10020384
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
902
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chrX
Cytoband
p11.3
Reference genome
GRCh37/hg19
Start
45522632/45663387 (Hg38)
End
45523680/45664435 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1587/Upstream/5825774; hsa-let-7f-2/Downstream/81722;
Nearest TSS
ENST00000429181/Upstream/152903; ENST00000464900/Downstream/100864;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/281206, chrX-CpG: 104/Downstream/186404
Upstream sequence
ctaaccctaaccctaaccctaaccctaaccctaaccctCTGaaagtggacctatcagcaggatgtgggtgggagcagattagagaataaaagcagactgc
Downstream sequence
tttacagagagctgattggtccgttttgacagggtgctgattggtgcatttacaaaccttgagctagatacagagtgccgattggtgtatttacaatccc
Target sequence
GGTATTAGGATCCACAGGAAGCCACATGTCAGAGTCACATTGCTCACATCAGCCCTTATTGTGTCTTGGTTTATCTTTTGTCACCTACTAAAGAGCATGGCAAGAAAAGGGTCAtggagaggcagcattctggagtcaagctgacctgggttcaaatcttgattctgtcactcctcagatatgagacgtcaggcaaatgccttaaatgctctgaactccaatttcctAAATATGTCCTTAATAAATAGTGGCTAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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