Basic Information
VIS ID
TVIS10020385
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
887
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
29537786/29384853 (Hg38)
End
29538834/29385901 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1244-3/Upstream/3510774; hsa-let-7i/Downstream/12937799;
Nearest TSS
ENST00000382841/Upstream/3664; ENST00000641955/Downstream/3388;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/3478, chr12-CpG: 66/Downstream/3384
Nearby gene
ERGIC2(-3643) ; OVCH1-AS1(+4441) ;
Upstream sequence
CCCAGGTCTGGCCAAGCCCCAGGATTAGAATAACCGATGCTTGACATTGATTTCAAATAAATTTCATGTCTCTGTCTGTATGAagtggtttttaaccctt
Downstream sequence
attggtgcattcgcaaactctgagctagacacggtgctgattggtgtgtttacaaaccttgagctagatacagagtgccgattggtgtatttacaatccc
Target sequence
aagaggaagtttgtctgacaggcattaggacccagggggcaagggtcaggatagataggatagatgggcgagtctcgcttgggcgacatgcttttgagagttctgctcatggccgcagggtcaaccaacttgttgtcgggaccccagagctgcatggctttcctctctgtcgaccctcggctcagcccagaagtactggaaaagcagaagctggttctagggaaaacaatggtcccaactccgaagagtcggggg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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