Basic Information
VIS ID
TVIS10020387
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
885
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
206842449/205977725 (Hg38)
End
206843497/205978773 (Hg38)
Orient
+
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/16844614; hsa-mir-1244-1/Downstream/804461;
Nearest TSS
ENST00000437798/Upstream/213388; ENST00000422116/Downstream/10812;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/51615, chr2-CpG: 85/Downstream/106215
Upstream sequence
tcccctgcctcagcctccccgagtagctgtgactccaggcacgcaccactatgcccggctaattttttgtattttagtagagacaaggtttcaccacgat
Downstream sequence
tcccatgtgttgtgggaggaacccagtgggaggcaatcaaatcatgagggcaggtctttcccatgctgttctcatgatagtgaataagtctgatgagatc
Target sequence
agtctggtggggacttggagaatctttatgtctagctaaaggtttgtaaatgcaccaatcagcactctgtgtctagctcagggtttgtaaatacaccaatcgacactctgtatctagctaacctagtggggacatggagaacttttgtgtctcactcagggattgtaaacgcaccaatcagcaccctgtcaaaatggaccaatcagctctctgtaaaatggaccaattagcaggatgtgggtggggccagataag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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