VISDB Viral Integration Site DataBase

VIS ID

TVIS10020389

Fusion event

HBV-SNTG1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

902

Orient

+

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr8

Cytoband

q11.21

Reference genome

Start

End

50988914/50076354 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-2681-5p ; hsa-mir-548c-3p ; hsa-mir-7977 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3671 ; hsa-mir-6849-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p

Nearest miRNA

hsa-mir-124-1/Upstream/7179031; hsa-mir-10400/Downstream/11638434;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/165006, chr8-CpG: 98/Downstream/1332248

Upstream sequence

AATGAATTTCCCAGAATGCACAGATGCTGCACCTAATCCCTTGGAGTTTAACCAGCACAAGAGTTTGCACTTTGCTGGCCATCTCCTGCCAAGGCACAGC

Downstream sequence

GTATACTATTAATGTTTAAGGTTGGACAATGTAGGTTCTATAAAAATGTATGAATTCCAATGCAATGAATTGGTCCAGAATAAAATTGTTTCTTTCCAAG

Target sequence

cagcaaggctcctgagtcgggaggagacttggagaacttttatgtctggctggaggattgtatatgcaccaatcagcactctgtgtctagctctgggttcatgtatgcaccaatcagcactctgtgtctagctaatctggtggagacttggagaacttttgtgtctaactcagggattgtaaacgcattaatcagcaccccgtcaaaacggaccaatcagctttctgtaaaatggaccaatcagcaggatgtggg