VISDB Viral Integration Site DataBase

VIS ID

TVIS10020391

Fusion event

HBV-EYS integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

45

End

1141

Orient

+

Integrated sequence

CCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCC

Chromosome

chr6

Cytoband

q12

Reference genome

Start

End

65257326/64547433 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p

Nearest miRNA

hsa-mir-10398/Upstream/7156173; hsa-mir-10524/Downstream/6829527;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/909825, chr6-CpG: 22/Downstream/753927

Upstream sequence

ctctactaaaaatacaaaattagctaggcgtggtggtacctgcctgtaaccccagctactcgggaggctgaggcaggagaatcacttgaaccccggaagt

Downstream sequence

gtagatacagagtgttgacgcaaaggttctccaagtacccaccagagtagctagatacagagtgtcgattggtgcattcacaaaccctgagctagacaca

Target sequence

acttaaatgttagacctaaaaccataaaaaccctagaagaaaacctgggcaataccattcaggacataggcatgggcaaggacttcatgtctaaaacaccaaaagcaatgacaacaaaagccaaaattgacaaatgggatctaattaaactaaagagcttctgcccagcaaaagaaaccaccatcagaatgaacaggcaacctacagaatgggagaaagtttttgcaatctactcatctgacaaagggctaatat