Basic Information
VIS ID
TVIS10020392
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
886
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
142525325/141604172 (Hg38)
End
142526373/141605220 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/16096865; hsa-mir-1305/Downstream/1738240;
Nearest TSS
ENST00000502981/Upstream/28095; ENST00000505351/Downstream/31379;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/382967, chr4-CpG: 69/Downstream/31015
Upstream sequence
CTCTCATTTAATCCCGAGGACATTGAGACAGTTGTGTTTGTGCACATTTAGGAGAAAATATAAGGAGAACCCTGATTATTCCTGTTATAAGTATTATGTG
Downstream sequence
ccactagatttgctagatacagagtgctgactggtgcatttacaaaccttgagctagatacagagtgccgattggtgtatttacaatcccctagctagac
Target sequence
attaagtctcaatctcttatgggcatgttcctctcatctatagccttcacaacgcttcttagtttcctcccctatcccctttgagataggaagatttgagagggctaaagttgggcatttcactttccacaggtcggttaagctccggtaaagcccatatttgttaagctctggtaaaatattttctcataagagcaggcttttgttcagaaaaacggaatgctctgggaatatttcagaacggctacttgttcc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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