Basic Information
VIS ID
TVIS10020397
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr3
Cytoband
q23
Reference genome
GRCh37/hg19
Start
140927372/141208530 (Hg38)
End
140928420/141209578 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/6770624; hsa-mir-1224/Downstream/10356298;
Nearest TSS
ENST00000440867/Upstream/84348; ENST00000511968/Downstream/19148;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/113238, chr3-CpG: 154/Downstream/21491
Upstream sequence
AAAGCTACCATTTTTTCTTTATCTGATCTTCTCACTACATGTATGTCTGCCCCCACATGCTGCTGCAGAGGAAATGAGTGCAGTGAGAGCATGCATGTGG
Downstream sequence
tccttagtgaacaactgctggctttgcatttccctttcttccagtgcctacacagctgtccccgccttacagacagactgagcaacatcttctgtctcct
Target sequence
ctaacaaaaccattatataaactcaccaaaggaaacctagctgaccccatagatcctaaatcctttccccactccttcttccattccttgaagacagctttagagactgcccccactctagctatccctgattcatcccaacccttttcattacccacaaccaaagggcaatgctgtgcagtcagaattcttacacaagaactgggactgcgccctgtagcctttttatccaaacaacttggccttactgttttg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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