Basic Information
VIS ID
TVIS10020399
Fusion event
HBV-WDR11-AS1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr10
Cytoband
q26.12
Reference genome
GRCh37/hg19
Start
122607754/120848242 (Hg38)
End
122608802/120849290 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
WDR11-AS1
Nearest miRNA
hsa-mir-107/Upstream/889650; hsa-mir-202/Downstream/1567675;
Nearest TSS
ENST00000439456/Upstream/17654; ENST00000470052/Downstream/1885;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/390377, chr10-CpG: 32/Downstream/1876
Upstream sequence
ggtcagagtgccatgtgactcccggttcgttagctccagcagggaagcaagtcaaagagagctagtgtccccggttcaatgcctaactagaattctgcct
Downstream sequence
taggtgtcagtgaaacctttatatcccttacaggcctccgtcttcaagaaaagtagaacggactaaaggtcttttaaaaagacagctcaccaagctcagc
Target sequence
ccaaatttcatcctcatctgttacctatctcggcataattctcataaaaacacacgtgctttccctgctgatcgtgtccgattaatctcccaaacctcaatcccttacaaaacaacaactcctttccttcctaggcatggttagtgcggtcagaattcttacacaacagccaggaccgcaccctgtagcctttctgtccaaacaacttgaccttactgttttagcctagccctcatgtctgcgtgcagcggctgc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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