Basic Information
VIS ID
TVIS10020400
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1706
End
2802
Orient
+
Integrated sequence
TTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTT
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37/hg19
Start
115856145/116722177 (Hg38)
End
115857193/116723225 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/1898613; hsa-mir-105-1/Downstream/1663169;
Nearest TSS
ENST00000429181/Upstream/27989; ENST00000493448/Downstream/1224717;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/753113, chrX-CpG: 74/Downstream/1393045
Nearby gene
LOC105373320(+4759) ;
Upstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Downstream sequence
ggagagcatgtgtgtttttatgagaattatgctgagataggtaacagatgaggaagaaatttgggcttgactgaagtaatgggggctgtctgtgaaggct
Target sequence
ggagatgttgcctagtctgcatgtaaagcggggacagctgtgtaggtgctggaagaaagggaaatgcaaagccagtggttatttgctaaggagggattagaaacggctaggagagaatgagtaaggttgatagtgtggtggagttagctggggagaggtagagggtggcataagaatgggaatgagaataagagtgagtataaaagtaaagaatagaacttcatcagggtgaaagtattggagggttccctgcca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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