Basic Information
VIS ID
TVIS10020401
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37/hg19
Start
115856087/116722119 (Hg38)
End
115857135/116723167 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7f-2/Upstream/1898555; hsa-mir-105-1/Downstream/1663227;
Nearest TSS
ENST00000429181/Upstream/27931; ENST00000493448/Downstream/1224775;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/753055, chrX-CpG: 74/Downstream/1393103
Nearby gene
LOC105373320(+4817) ;
Upstream sequence
AATGATGTAGAGTTCATGCAGAAAAAAATACAACAAAAACCAAGGGAACATAGAATTGGAAAACGCGTCACAGCAATGAGTTAAATAGGTAACAAATTTC
Downstream sequence
agttgttgttttgtagaaggtgttggggtttgagagatcagtcggacacaatcagcagggagagcatgtgtgtttttatgagaattatgctgagataggt
Target sequence
ttcctcaggagggtaaaggtgagggctgttaaaggaagttcggaggagcagggagacaggagatgttgcctagtctgcatgtaaagcggggacagctgtgtaggtgctggaagaaagggaaatgcaaagccagtggttatttgctaaggagggattagaaacggctaggagagaatgagtaaggttgatagtgtggtggagttagctggggagaggtagagggtggcataagaatgggaatgagaataagagtga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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