VISDB Viral Integration Site DataBase

VIS ID

TVIS10020405

Fusion event

HBV-PCDH11X integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1706

End

2802

Orient

+

Integrated sequence

TTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTT

Chromosome

chrX

Cytoband

q21.31

Reference genome

Start

End

91357473/92102474 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-376a-2-5p ; hsa-mir-3935 ; hsa-mir-2115-3p ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-432-3p ; hsa-mir-4775 ; hsa-mir-324-5p ; hsa-mir-1306-5p ; hsa-mir-590-3p

Nearest miRNA

hsa-let-7f-2/Upstream/6197719; hsa-mir-105-1/Downstream/2960667;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/319156, chrX-CpG: 20/Downstream/1571073

Upstream sequence

aaggagaaaggttttttaagtaagtgctgaggagggcggcagcttgctgatatgaaatgtctggggaggtcttgctggacctgcctagaaagtaaatgag

Downstream sequence

attgaggtttgggagattaatcggacacgatcagcagggaaagcatgtgtgtttttaggagaattatgccgaaataggtaacagatgaggatgaaatttg

Target sequence

ggctgagcttggtgaggtgtgtttttaaaagaccttagtccattctacttttcttgaagatggaggactgtaagggatataaaggtttcactgaatactaacagcctgaaaaactgcttggctgatttgactaataaaggcttatctgttatcagactgtattgaggtgggaaggctaaactgaggaattatgtctgacagaacggaagaaatgactgcggaggccttctcagaccctgtaggaaaggcctttac