Basic Information
VIS ID
TVIS10020407
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
80836164/81125121 (Hg38)
End
80837212/81126169 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10392/Upstream/1702895; hsa-let-7a-2/Downstream/764572;
Nearest TSS
ENST00000527297/Upstream/362295; ENST00000526154/Downstream/844825;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1683961, chr11-CpG: 25/Downstream/1563374
Upstream sequence
AGAAACCGATTCTTCACCTTAGAGGGAGGAGACTTGGAAAGGAGCCGAGCATGGGTGAGCACTCAAAGATTCAGGCTGGCTGTGTGATCGATGCTAGGAC
Downstream sequence
ctatacagtctgataatggaccagcctttactagtcaaatcagccatgcattttttcaggctcttggtattcagtgaaacctttatatccctaacggtcc
Target sequence
gctaagcaaactaactaagctgtactgccacaaggcttcacagacagccctcattacttcagtcaagcccaaatttcttccccatctgttacctatcttgtcataattctcataaaaacacacatgctctctctgctgatcatgtccggctaatctcccaaaccccaatcccttctacaaaacaactcctttccttcctaggcatggttagtaaggtcaaaattcttacacaagggccaggaccgcgtcctgtag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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