Basic Information
VIS ID
TVIS10020409
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
57459439/57232304 (Hg38)
End
57460487/57233352 (Hg38)
Orient
-
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/1231509; hsa-mir-10b/Downstream/3154010;
Nearest TSS
ENST00000437798/Upstream/1046534; ENST00000463222/Downstream/674299;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1046900, chr2-CpG: 81/Downstream/813155
Upstream sequence
ATATTAGCACCTTTAAACACCTAgtcttgtttattaactctttgttcaggcccagaatactgatttacacatagtagatcctaaataaatattctttgaa
Downstream sequence
cagctgtccctccttacatgcagactaggcaacatcttctgtctccctacacctccgaacttcctttaacagccctcacatttaccctcctgaagaactc
Target sequence
atctgttacctatctcagcataattctcataaaaacacacgtgctctccctgccaatcgtgtctgactgatctttcaaaccccaaaaccttctacaaaacaacaactcctttccttcctaggcatggttagtgcggtcagaattcttacacaagagctgggactgtaccctgtaggctttctgtccaaacaacttgaccttactgttttagcctggccctcaggtctgcgtgcggcggccgccgccaccctaata
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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