Basic Information
VIS ID
TVIS10020410
Fusion event
HBV-LOC105375100 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
55876868/56012070 (Hg38)
End
55877916/56013118 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375100
Nearest miRNA
hsa-mir-10398/Upstream/2734999; hsa-mir-10524/Downstream/1377014;
Nearest TSS
ENST00000381078/Upstream/136506; ENST00000426453/Downstream/48059;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/432776, chr6-CpG: 19/Downstream/234272
Upstream sequence
cggtggctcacgcctgtaatcccagcactttgggaggctgaggcaggcggaccacctgaggtcaggagtttgagaccagcctgaccaacatggagaaacc
Downstream sequence
gagataggtaacagatgaggaagaaatttgggcttgactgaagtaatgggggctgtctgtgaagccttgcggcagtacagcctaggtaatttgctgaggc
Target sequence
ggggacagctgtgtaggcgctggaagaaagggaaatgcaaagccagtggttgttcgctaaggacggattagaaacggctaggagagaatgagtaaggttgataatgtggtggagatagctggggagaggtagagggtggcataagaatgggaatgagaataagagtgagtataaaagtaaagaatagaacttcatcagggtgaaagtatcggagggtcccctgccagcaaagatcatctatccactctaagaggg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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