Basic Information
VIS ID
TVIS10020412
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
53533221/52959086 (Hg38)
End
53534269/52960134 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-15a/Upstream/148946; hsa-mir-1267/Downstream/1351838;
Nearest TSS
ENST00000623511/Upstream/110445; ENST00000219022/Downstream/68625;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/107226, chr13-CpG: 217/Downstream/239995
Upstream sequence
TAATAAAACCTGTCTGCTGTGTACCCAGAGTTTATAATAGAATTCATCCTAATTCTCTTCTTTTTGGGGTTATTTCTTATGTCAGGTCTAGTACCTGCCA
Downstream sequence
TCCTGTGAGTCTGGGTTAGCTTGGGGTGCCAATGAAGAGAAATGTGCTAACAATGCACTGTGGTTTCCATTTCCACCTCGTCTATCCAGGAGCAGTTAGA
Target sequence
aagaggttatgaaatgacgacagaatagaataggcctgtaagactggaaggagatattttctttggtccaagaaccatttgccttgtgtgggaagagattgataggtggaagtttcagtgggggagtaggtgggagtgaccagatgagaaggagaaaaactgccatgaggaatagaagttggaaaaagctagctgctttttagctaccttattagcataagcattgccctgagtgatgggatctgatgccttttg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate