Basic Information
VIS ID
TVIS10020414
Fusion event
HBV-ISX-AS1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
35233639/34837648 (Hg38)
End
35234687/34838696 (Hg38)
Orient
+
Location type
Intronic
Target gene
ISX-AS1
Nearest miRNA
hsa-mir-1286/Upstream/1400979; hsa-let-7a-3/Downstream/496944;
Nearest TSS
ENST00000624155/Upstream/112729; ENST00000404699/Downstream/164166;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/914999, chr22-CpG: 76/Downstream/418672
Upstream sequence
ctgttctggatctcaaacatgctttctttactattcctttgcacctttcatcccagcctctcttcgctttcacttggactgaccctgacacccatcaggc
Downstream sequence
cctacctctatacagtctgataatggaccagcctttattagtcaaaccagccaagcattttttcaggcttttggtattcagtgacacctttatatccctt
Target sequence
tcagcaaattacgtgggctgtactgccacaaggcttcacagacagcccccattacttcaatcaagcccaaatttcttcctcatctgttacctatctcggcataattctcatgaaaacccacgtgctctccctgctgatcgtgtctggctaatctcccaaaccccaatcccttctacaaaacaacaactcctttccttcctaggcatggttagtaaggtcaaaattcttacacaagtgccaggactgcgtcctgca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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