Basic Information
VIS ID
TVIS10020418
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1204
End
2300
Orient
+
Integrated sequence
GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
34923346/34698279 (Hg38)
End
34924394/34699327 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01320 ; LOC107985865
Nearest miRNA
hsa-mir-1301/Upstream/1279715; hsa-mir-10b/Downstream/772078;
Nearest TSS
ENST00000437798/Upstream/3981; ENST00000607437/Downstream/4279;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/970662, chr2-CpG: 191/Downstream/1655927
Upstream sequence
atgttgttaagtgacacatgagtgCATTTCCCATGTGTTGTGTACAGATGTATTACCAAAAAAAGAACCTTTTATTTACTTTTCACGTAGAAACATACTG
Downstream sequence
gtagaagggattggattttgggagattagtccgacatgatcagcagggagagcacgtgtttttatgagaattatgccaagatagataacagatgaagagg
Target sequence
taaaggtgagggctgttaaaggaagttcagaggtgtaaggagacaggagatattgcccagtctgtgtttaaggtggagacagctgtgtaggcactggaagaaagggaaatgcaaagccagcagttgttcgctaaggagagattagaaatggctaggagagaatgagtaaggttgatagtgtggtggagatggctggggagaagtagagggtggctaaagaatgggaatgagaataagagtgactctaaaagtaaa
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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