VISDB Viral Integration Site DataBase

VIS ID

TVIS10020422

Fusion event

HBV-IL1RAPL1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1204

End

2300

Orient

+

Integrated sequence

GTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACC

Chromosome

chrX

Cytoband

p21.3

Reference genome

Start

End

28912933/28894816 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-151a-5p ; hsa-mir-4307 ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6840-5p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-7108-5p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-663b ; hsa-mir-5197-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-4279 ; hsa-mir-100-3p ; hsa-mir-539-5p

Nearest miRNA

hsa-mir-23c/Upstream/398105; hsa-let-7f-2/Downstream/679462;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/1029713, chrX-CpG: 30/Downstream/1352239

Upstream sequence

cctacacagaagaggttatgaaatgatgacagaacagaatgggcctatgaggctggaaggagatattttccttggtctaagaaccatttgccttgtgtgg

Downstream sequence

ctaggaaagaaaggagttgttttgtagaagggattggggtttgggagattagccggacacgatcagcagggagagcacatgtgtttttatgagaattatg

Target sequence

tacacagaagaggttatgaaatgatgacagaacagaatgggcctatgaggctggaaggagatattttccttggtctaagaaccatttgccttgtgtgggaagagattgataggtggaagtttcagcgggggagtaggtgggagtgaccgatgtgaaggagaaaaactggccatgagggacagaagttggaaggctagctgcttgtctagccaccttatcagcataagcgttgcctagagcaatgggatctgacgc