WFDC3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020424
Fusion event
HBV-WFDC3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1199
End
2295
Orient
+
Integrated sequence
CACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGA
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
44391620/45762981 (Hg38)
End
44392668/45764029 (Hg38)
Orient
+
Location type
Intronic
Target gene
WFDC3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/57801; hsa-mir-1-1/Downstream/1402938;
Nearest TSS
ENST00000382410/Upstream/40630; ENST00000449078/Downstream/15864;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/275294, chr20-CpG: 46/Downstream/27829
Upstream sequence
GTCAAGCGACCTTTAAAGATGACCAGTCGAGTATAATAGTGCCACTCAGACATTTGCCATCAGTAACTATTATTATTAAATTATACTCATTTgctgggcg
Downstream sequence
cagtttagctttcccacctctatgcagtctgataacagacgagcctttattagtcaaatcagccaagcagtttttcaggctcttagtagtcagtgacaga
Target sequence
cctgacacccattaggctcagcaaattacctgggctatactgctgcaaggcttcacagacagcccccattacttcagtcaagcccaaatctcatcctcatctgttacctatctcggcataattctcataaaaacacatgtgctttccctgctgatcatgtccgattaatctcccaaacctcaatcccttacaaaacaactcctttccttcctaggcatggttagtgcagtcagaattcttacacaagagccagga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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