VISDB Viral Integration Site DataBase

VIS ID

TVIS10020435

Fusion event

HBV-CPS1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1175

End

2275

Orient

+

Integrated sequence

CCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGT

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

211422070/210557346 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-17-5p ; hsa-mir-3121-3p ; hsa-mir-4255 ; hsa-mir-4709-3p ; hsa-mir-7154-5p ; hsa-mir-101-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-8060 ; hsa-mir-16-1-3p ; hsa-mir-144-3p ; hsa-mir-216a-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-6516-5p ; hsa-mir-6738-3p ; hsa-mir-1303 ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-1200 ; hsa-mir-142-3p ; hsa-mir-630 ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-7976 ; hsa-mir-496 ; hsa-mir-302a-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-4682 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-4778-5p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10b/Upstream/2801415; hsa-mir-1244-1/Downstream/1868917;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/79484, chr2-CpG: 86/Downstream/1980110

Upstream sequence

ctctctctttctGTGTCATTCTCCATGTTTGTCCTTCTGTTCCCTTTCCTTGTCTGTCTCTGCACACCAAGGTTGCTCCCAGCTGGGAGGTTGGCCCTGT

Downstream sequence

GTCATCATGTAGACACTGCTTTAGCTTTTTCCTTTTCCTTCTGGCTGTTTTTTTGGGCAGGCTAAACTTATTATTTTCATTTTGTAGAGTAATACATAGA

Target sequence

GGTATCACATGTGACATAAGCAAAAGCCTGTGATCCTTAGCATGTTGGAAAGTTGCTACTCTTTAGGATAAGGTTGTCCATGATGTCTAGGTCATTCCATTCAGCTGCATAAACAATTCCTTTGATGGATGGCTGGTTTTCTACAACCCCAGCATTATTTTAGCAGGAGAAGGTAGTATTTGATGTGTTGCAATTTGTGTTACATGCCCATGGAACATCTCTGGACATTACCTCAGGAGGAGGGGTTAAGAGAAG