VISDB Viral Integration Site DataBase

VIS ID

TVIS10020437

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1175

End

2275

Orient

+

Integrated sequence

CCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGT

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216250447/215385724 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1626515; hsa-mir-1244-1/Downstream/2514789;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/72265, chr2-CpG: 43/Downstream/49820

Upstream sequence

tatactttctgctccctggcttcttcagctgtactcactctttgttgagtctcccacaattaccattgttcctggcccagacttcaatccggcctcccac

Downstream sequence

tacCCTAAAATTATATTTTTAAAGGTACTTTGAAACAGTGTTCAGTTTTCCACCttttttttttttttttttgagacagagtctccctctgtcaccaggc

Target sequence

TTTTTATTTGGGTTTTAGAACAAATTATATCATCTATATCTTACGTATTTTCTTGGAAAAAACAAGGGCTCCGTTGAATGGACTTGCCAAAGTTTCTTTAATTCTTTGTTCACTGTTGGGCTTTCAGGTTATCCACAACAGAATCTGATTTAATCAGAGTGTAAAATAGCATTTTACTGCTGTACCTGTCTCTCCGTAAGTGATCCTGTAATATCTCACTGTGACAGCAGGAGCATCCCAGCTGATCAGTAGGCT