Basic Information
VIS ID
TVIS10020439
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1140
End
2240
Orient
+
Integrated sequence
CTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCC
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
GRCh37/hg19
Start
103704386/103256511 (Hg38)
End
103705436/103257561 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10398/Upstream/4131815; hsa-mir-1202/Downstream/3526564;
Nearest TSS
ENST00000381078/Upstream/1328368; ENST00000635857/Downstream/1474809;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1853413, chr6-CpG: 79/Downstream/1601683
Upstream sequence
TTTATTTTTCTAGTGCATCTCACAAAATCAGCTCTCTCTGGCTCCTTTGTTTAAATTCGGAACTAATTCCTCAAAACTATGTGAAAGTGGAAATTATAAG
Downstream sequence
CCATTTGGAAAATTCATTTCTCAGCAGTAGGAAAATTCTTGGAAGTTCGAATGTTGTAAGAAGTCAAAACCAAACACGTATCATATTTACATATTAGCTT
Target sequence
TAAAGTCATCTTTTTTTTACACACAAACGTGCACACACAAATACATAACAATTTCTTACTTATATTTGTGAAGTGGTTTTGTGTATCTCTGCATATTTGTTTTCCTTAACATACTATATATAGAGACCTTTACTGAAATATTTAAATTACAAAAGCTCAAAGATTGTTATTAATGTTAAAGTAGCATTTTAAAAAATCTAAGATTCAAAAACGTGTCAATAATGAGataaattataaataattatttaaCTATTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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