VISDB Viral Integration Site DataBase

VIS ID

TVIS10020446

Fusion event

HBV-COQ7 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1070

End

2170

Orient

+

Integrated sequence

TATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTAT

Chromosome

chr16

Cytoband

p12.3

Reference genome

Start

End

19084669/19073347 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-942-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-224-5p ; hsa-mir-6879-3p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-137 ; hsa-mir-4742-3p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-3671 ; hsa-mir-3926 ; hsa-mir-216a-5p ; hsa-mir-1267 ; hsa-mir-1304-3p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-3650 ; hsa-mir-3652 ; hsa-mir-3664-5p ; hsa-mir-367-5p ; hsa-mir-3689d ; hsa-mir-4423-5p ; hsa-mir-4430 ; hsa-mir-4639-3p ; hsa-mir-4695-3p ; hsa-mir-5007-5p ; hsa-mir-6128 ; hsa-mir-613 ; hsa-mir-6499-3p ; hsa-mir-6501-5p ; hsa-mir-6787-3p ; hsa-mir-6794-3p ; hsa-mir-7151-3p ; hsa-mir-744-3p ; hsa-mir-7641

Nearest miRNA

hsa-mir-1225/Upstream/577721; hsa-mir-11401/Downstream/2432702;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/4231, chr16-CpG: 47/Downstream/13062

Upstream sequence

tttaccatcctgactaaaccattatataaactcacaaaagcaaacctagctgaccccacagagcctaaatcctagctgaccccacagagcctaaatcctt

Downstream sequence

ccaggtgtagtggcatgtgactgtaatcccagctaatttgagaggccgaggtgggaggatcgcttgatcctggaggttgaggctgcggtgagccatgagc

Target sequence

acatctagtacatagacaggtatgcggtatatctttggtatcagtactccatggcgggggcaggcagtaatgaaaaaaGGTTAAGAATCGCTCAGCACAGCAGTCAACTGTGCTGAAATGTTGCAGCCCTGCCCCCTACCGTGCcagagaggtattgtatcccaagaggctatgggaggacctgaaatttgtagttacacagacctggttcacattttggctctctcccacctcctacctgtgcgaccttgagga