Basic Information
VIS ID
TVIS10020447
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
947
End
2047
Orient
+
Integrated sequence
TCGAAAATTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCAC
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
38697512/38303710 (Hg38)
End
38698562/38304760 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1244-3/Upstream/12429631; hsa-let-7i/Downstream/4018940;
Nearest TSS
ENST00000382841/Upstream/4084857; ENST00000553138/Downstream/11818;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/139819, chr12-CpG: 25/Downstream/11830
Upstream sequence
CAATAGTCATTTTAAAAGTATGGCATCCCTTCTTGTTCTTGTTTACAATTAGTTCTCtttattccatttattattaagtactgtgctgagagttttactt
Downstream sequence
TCACCATAAATAAACAAATCAAATTTTAATTATTGTTGTTCTATGAATAATGACCATCAATTTTTAGGTTAAAATATTTTGATTTATTAATCATGCTAAA
Target sequence
tgtccagactgttctcaaaatcctgagctcaagcgatctgcccacctcagcctcccagagtgctgggtttacagacgtgagccactgtacgaggccAGTGTTCATATTTGCTATAGTTTTATGATACCCAAAAGCTCTCACCATCTTTCAATATTCAAATTATGCATTGGGAAACATTTATGAGTAGGATGGTCAGCCATGTTATCATTGGGCCTCCACACATCGCCAGCCTGGGTATAAACATAAAATCAAACA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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