VISDB Viral Integration Site DataBase

VIS ID

TVIS10020450

Fusion event

HBV-GALNTL6 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1110

End

2160

Orient

-

Integrated sequence

AAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACC

Chromosome

chr4

Cytoband

q34.1

Reference genome

Start

End

173137128/172215977 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6844 ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-12113/Upstream/1028635; hsa-mir-1305/Downstream/1052183;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/400960, chr4-CpG: 154/Downstream/952815

Upstream sequence

acacacacacaGAGTCCACAGCCACAAGTGTCTCTGACCAGCCAGTGTTGCTGAGGCTGCACCTCAGTCTTCGTGGTGTTCACAAACTAAGGGGATTCTG

Downstream sequence

cccttggaacattgctgccattcattttatctgttcatatgttatatacacccaatatgttgttgctaatattactttaaacaaaccattatttcttagg

Target sequence

ttagttgctattaatttacctccagagcataccacaatttttgatgttttattttcatttagttcaaatttctctgaggtatttatggactcatgtacagtatagaaatgtgttatataatctccaagtatttggagatttttacctcagtctttccctgattaatttatagtttaattcctttataacccgagaaaattatttgtatgatttctattctttttaaatttggtgtgtttcgtggcttatgatgta