VISDB Viral Integration Site DataBase

VIS ID

TVIS10020451

Fusion event

HBV-chr11 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1151

End

2251

Orient

+

Integrated sequence

TGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCT

Chromosome

chr11

Cytoband

q24.1

Reference genome

Start

End

123522454/123651746 (Hg38)

Orient

+

Location type

Intronic

Target gene

LOC105369543 ; SCN3B

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1228-3p ; hsa-mir-1273e

Nearest miRNA

hsa-let-7a-2/Upstream/269184; hsa-mir-3167/Downstream/3336712;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/73022, chr11-CpG: 96/Downstream/2279

Upstream sequence

gtttttttttttgttgttgtttatttgtttgttttgtttttAAATTTTTAGTTTGACAGGCTATTTCCCTTTTGTTTTCATATTTTCTGTTGTCTCTCCC

Downstream sequence

GACAACACTCAGTTTGCAAAGAAACTGAGAATGGGCAAAGATGGGCATACTGTGTACACTTCTTCCAAAGTTTTTTGGGGTCGGGGAGGGGATGGGCACT

Target sequence

ACATGTGTCCATGAGAGGTGCTAGAAGGAGCACTGGAAGACTGAAATCAGAAAACAAGGGTTCTCTAgcaagtcctttcccttccccgagctcattttctcatctctaaactggaaatagcactctttcccctgactacctcagggatagacatgaggaccaaaacaagcaatgtattgaaaattacattgtaaactgtgatgcacaggcaaatatagggttttatttatttatttattttaaaggctgggcatg