Basic Information
VIS ID
TVIS10020452
Fusion event
HBV-LOC105375670 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1106
End
2206
Orient
+
Integrated sequence
TTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATA
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
101458910/100446682 (Hg38)
End
101459960/100447732 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375670
Nearest miRNA
hsa-mir-12123/Upstream/63837; hsa-mir-10400/Downstream/255236;
Nearest TSS
ENST00000518652/Upstream/15685; ENST00000521851/Downstream/27943;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/136196, chr8-CpG: 62/Downstream/111555
Upstream sequence
tttttgagcactgccttaccttttgaccccacaagatattctaggctcagtgtacactttgcctggtccagccctggaatcagccattgctgctgtgcta
Downstream sequence
cctctattattgccttcttttgtgactaattgatttttttgcatagtgaaaggttttgatttccttttcatttccttttgtctatattctctaaatattt
Target sequence
tatggtaattctatatgtaactttttgaggaacgactaaactgtttttcacactggctgcaccattttacattcccactagcaatgtatgaaggttccaacttctccatattcttgccaacacttgttattttctattttttaaaaattctaaccatccttgtagatatgaagtggtatcttgttggggttttgatttgtatttccttaatgactactgatattgagcatcttttcatgtgtttattggccattt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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