VISDB Viral Integration Site DataBase

VIS ID

TVIS10020453

Fusion event

HBV-NCOR2 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1115

End

2211

Orient

+

Integrated sequence

CTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTT

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

124913694/124429148 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-16-5p ; hsa-mir-9-5p ; hsa-mir-2110 ; hsa-mir-130b-5p ; hsa-mir-20a-5p ; hsa-mir-125b-5p ; hsa-mir-100-5p ; hsa-mir-30c-5p ; hsa-mir-4459 ; hsa-mir-6757-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-3178 ; hsa-mir-6799-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-658 ; hsa-mir-2277-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6087 ; hsa-mir-6871-5p ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-4739 ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-34a-3p ; hsa-mir-1266-5p ; hsa-mir-3197 ; hsa-mir-3612 ; hsa-mir-3937 ; hsa-mir-4274 ; hsa-mir-4313 ; hsa-mir-4443 ; hsa-mir-4518 ; hsa-mir-4530 ; hsa-mir-4802-5p ; hsa-mir-510-5p ; hsa-mir-6085 ; hsa-mir-650 ; hsa-mir-6798-5p ; hsa-mir-6807-5p ; hsa-mir-6813-5p ; hsa-mir-6858-3p ; hsa-mir-7108-3p

Nearest miRNA

hsa-let-7i/Upstream/90858; hsa-mir-3612/Downstream/486399;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/1182, chr12-CpG: 28/Downstream/16178

Upstream sequence

agtaagatactagctgtgggtctgttgtatattgcttttactgtgttcaagtatgttccttctattccaagtgttttgagggttttatcatgaagggatg

Downstream sequence

GTGCTGGGAACTCTTCGGCCTGCGccatgctccccccaccctgccaggctctgggccctggaaggctgaccctggaacccacaggcactcccgccccttg

Target sequence

CAGCCCAGGTGCCACACCCTTGGCCATCAGGTGAGGAATGCAGAGGAGAGGGCCACCGGCCTCCTCCTTCCAGTGCAGACTAAACCCACAGCCAGCCTCTCTGCGGGATGTCCATAAGTGCACAGCATCGGTGAGACAGGGGCTGACACGGCCCAGCTCCGGCGCCCAGCCTTCGAGGGCCGGGCCCTGTGGCTGTGCAATGCGATGGCTTTCTGAGCTCTGTTTTCTGTCAACTGGATGTTGTTGTAAACAAAA