Basic Information
VIS ID
TVIS10020454
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1164
End
2260
Orient
+
Integrated sequence
TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
53830248/53326995 (Hg38)
End
53831296/53328043 (Hg38)
Orient
+
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/1045102; hsa-mir-10394/Downstream/338636;
Nearest TSS
ENST00000633603/Upstream/35369; ENST00000595091/Downstream/5703;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/18237, chr19-CpG: 17/Downstream/1075
Nearby gene
ZNF845(+6724) ;
Upstream sequence
AGCACCAGTCCCCTCTCCACCACGTGCCCCAACTCCTCCATCTACCCCAGTTCCACTCCCTGAGAAGAGACGGTCCATCCTAAGGGAACCCACATTTCGC
Downstream sequence
ATCCTAGGCCCAGGAAGAAGATGCAGCATTCAGGGCTGCACTTGAGAGGCCTAAAACGGTGAGGGAGGCAGAGCTCAAGAGCTTGACTCTATCTCCTGAG
Target sequence
ATACCCCTCTTTAGTTGTGCCCAGAGACCCATCCCTAGGAAACCCTCCTCCAGTGAAAACTACCAGTTTCCTGAGTCTTAGCCCCTCACTCTTTACCTTCTTTCTGGAGTCACACAATCCTGGAAGCTCCATGGGGTCCAATTCACTCTTGAGAGCCCATAATGATTCCCCCATTCTGCTATGAAATCCCACAGCACATTGCAAGCCCTAATAACATATCTATTCATGTTGTAATGACATACATAAATTGACCCA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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