Basic Information
VIS ID
TVIS10020455
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41392829/40996825 (Hg38)
End
41393877/40997873 (Hg38)
Orient
+
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1286/Upstream/182867; hsa-let-7a-3/Downstream/94640;
Nearest TSS
ENST00000624155/Upstream/30624; ENST00000637592/Downstream/93913;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/45070, chr22-CpG: 111/Downstream/23804
Upstream sequence
agacacgaggtgtggtgggaggagcatcctagctgggctctgcaggctgaggccaggaggctCCCACAGTGGTCCTGGTGGAGTCAGAAGGCCAGTTCTC
Downstream sequence
tcagtcttttgcccaggctggagtgcagtggcgtgatcttggctcgctgcaaccctcacctcccaggttcaagcaattctcatgcctcagcctccaaagt
Target sequence
CAGGCCCTGAAGCTCATTAATTTAGGTGCTCAAGGAGGGATTCGTCgttttattttgttttgttttgttgagagacagagtcttgctctgtcacccaggctggagtgccgtggcatgatctcagcttgctgcaacctctgcctcccgggttcaagtgattcttctgcctcagcctccctagtagctgggattacaggcatgcgccaccacacccagctagttttttatatttttagtagagacactgtttcacca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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