Basic Information
VIS ID
TVIS10020456
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1159
End
2255
Orient
+
Integrated sequence
AACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGA
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
5093037/5092924 (Hg38)
End
5094085/5093972 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-4277/Upstream/3384056; hsa-mir-10397/Downstream/1733881;
Nearest TSS
ENST00000502646/Upstream/14613; ENST00000511368/Downstream/46082;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/226407, chr5-CpG: 148/Downstream/45356
Upstream sequence
CCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAgggcggggccgcggaaaggaaggggaggggctgggaggg
Downstream sequence
gcctggggcagagcgagcccttggtggaagagaagcaggtgctcagcagctggaagtcagactagtctgctttgacattatggtacagaggagatgcagg
Target sequence
TCAAACTTGATGATTTTACTTTTATTGCTTTATATTGTGTATGTTTTACACACTTTTCCATGTTAAAAACTTGCCAAAAATAATGCTGGAATGTAATTATCAAATGAGGAGCACAACATTTGGGTCCAACTTTGTCAAGTAGCACCATGCCAACATGAACTGAGAGCCCTGTTTTCAGAGAACAAGCCAGGCATAGAGCTTTGCTCAGCAGATCCGTCAGCCTAGCACTTACTGGCTTCATGCAGGATCTTGCCC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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