VISDB Viral Integration Site DataBase

VIS ID

TVIS10020457

Fusion event

HBV-GALNT8 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1156

End

2252

Orient

+

Integrated sequence

GGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCG

Chromosome

chr12

Cytoband

p13.32

Reference genome

Start

End

4840705/4731539 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4446-5p ; hsa-mir-4804-3p ; hsa-mir-627-3p ; hsa-mir-7-2-3p ; hsa-mir-5688 ; hsa-mir-7-1-3p ; hsa-mir-495-3p ; hsa-mir-591 ; hsa-mir-676-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4289 ; hsa-mir-4714-3p ; hsa-mir-6769a-3p ; hsa-mir-501-5p ; hsa-mir-7151-5p

Nearest miRNA

hsa-mir-3649/Upstream/3070111; hsa-let-7i/Downstream/2232160;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/81226, chr12-CpG: 137/Downstream/77568

Upstream sequence

TCTTAGCTTCAGGATTTAGTTTAATATATTtcttacattatccttgtccttcaccatacatctggcttatagtaggaacttagtaaattattgaatTCAC

Downstream sequence

gcgagcattcttgtcttgttcctgaccttagaggaaaagctctcaatttttcctcattgagtatgatgttagctgtgggtttgtcatatgacctttattg

Target sequence

tgacatctttgttgaaaatcagttgcttataaatgtgtggatttatatctgtgttctatattctgttccactactctatgtctgtttttatggcagtatcatgctgttttgattaccatagcttaatatagtatattttgaagtcatgtagtgtaatgtctccagctttcttcttttggctaaagattgctttggctattcaggataatttatggttccatttagaacttttagagttgttttttctatctgtaa