PAPPA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020460
Fusion event
HBV-PAPPA2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1110
End
2206
Orient
+
Integrated sequence
AAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACC
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
176693508/176724372 (Hg38)
End
176694556/176725420 (Hg38)
Orient
-
Location type
Intronic
Target gene
PAPPA2
Nearest miRNA
hsa-mir-101-1/Upstream/755893; hsa-mir-1182/Downstream/303943;
Nearest TSS
ENST00000473358/Upstream/170884; ENST00000479836/Downstream/66025;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/516697, chr1-CpG: 44/Downstream/438836
Upstream sequence
GGTAAAAGGGGAGTGTGTCTTCCAGTTAATTTCACATTTTGGTTTCTCAGTTCTGGAGTAAACTAGTTTTATATTAAATTAAATCTGGCACACATCCCCC
Downstream sequence
AAACAATGCCTCATATGAACAATATATTGTGATATGGAgggatccaaagatgaatgaattaccatcttcacccttaaggtacatacatagcagtggGCAT
Target sequence
CTAAGTAATATAGACAACAAATGAAGCAATTTGAGAAGCAGATACTCAATAAGTACTTGTTTGGTTTCATAGGGAGCCCGTCAACATATGCAAAATCATATGTTCATGTTTATTTTCGTGGCTCCTCTAAAATGTCTGCAATTTGGAATGGTCTCGTTCAGGCTGGACTGGTTAGCAATCCCAACAGCAACCACCACATGCTCACAGTGTCTTCCACATCAGTTATAAATTACAGACCACTGCCTGGAAACCCTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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