Basic Information
VIS ID
TVIS10020467
Fusion event
HBV-LOC105371129 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1280
End
2376
Orient
+
Integrated sequence
CCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCT
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22097545/22086224 (Hg38)
End
22098593/22087272 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371129
Nearest miRNA
hsa-mir-1225/Upstream/580089; hsa-mir-11401/Downstream/2115844;
Nearest TSS
ENST00000527434/Upstream/1093; ENST00000562340/Downstream/2892;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/77488, chr16-CpG: 28/Downstream/75085
Upstream sequence
ctagggagatgccattgtctccaggagagcgaaggttggttcttggtggagatggggagcaaaaagcatattgttctttttatggataaagcacagagag
Downstream sequence
TTTCTGCTAAAAGGAATGGACTCGAGGATTTGATCTCATTTTAGATGCAGTTGTCCTCACTTGGCCATTTTACAGCACTTTAGTAAATATGGCCAGTGTA
Target sequence
catgttcacatttctgtcattcccattgtctacagaatgaaatccaaactcctttagcatagctttgacaagctttcgtgatctggcttcaagctctctgttcagtcatttcccacctctctctctcgtcacttcttactgacaaccagcctgttctccATTCTAGATTCACTACAACCTGCTCCCTGCCCCGGTTGTGTCTGTACCACCTCCTCTCAGTTTTAAAGTCCTCCCATATTTGAAATATATCTAATC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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