Basic Information
VIS ID
TVIS10020468
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1224
End
2320
Orient
+
Integrated sequence
CATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGC
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22117026/21648810 (Hg38)
End
22118074/21649858 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARL6IP1P1 ; TRA
Nearest miRNA
hsa-mir-6717/Upstream/625424; hsa-mir-1185-1/Downstream/1307092;
Nearest TSS
ENST00000550708/Upstream/5921; ENST00000408935/Downstream/3977;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/137253, chr14-CpG: 40/Downstream/939157
Upstream sequence
GTTACTTCATTTTCtttcttttcttttttttttttttttcgttttagagatggagtcttgctctgtggcccaggcgggagtgcagtggcgcgatctcggc
Downstream sequence
GAGAAGCAGGTTGTGGACTTGCTGTCCCATCCAAACAACTGCAGCGAGATAAATGATCATGGCCATGAAACACATTTCAGGCTTTTCTTCCTTCAGTGCG
Target sequence
TTGTTCCATCAGGATCCTTTTTCCATGGTAAAAAAGCAGAATGAGGAATGAAGGAATGAATCttttttttttttttttttttgagactgagtctcgctctgtcgcccaggctggagtgcagtggcgcgatcagggctcactgtaagctccgcctcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacaggtgcccgccaccacgtccagctaattttttttgtatttttagtagaga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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