VISDB Viral Integration Site DataBase

VIS ID

TVIS10020470

Fusion event

HBV-MYH15 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1246

End

2342

Orient

+

Integrated sequence

TTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATC

Chromosome

chr3

Cytoband

q13.13

Reference genome

Start

End

108201362/108482515 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4683 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-6888-5p ; hsa-mir-7161-3p ; hsa-mir-1207-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-4487 ; hsa-mir-4722-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-6077 ; hsa-mir-6776-5p ; hsa-mir-6861-5p ; hsa-mir-6868-5p ; hsa-mir-708-5p ; hsa-mir-7150 ; hsa-mir-7-5p

Nearest miRNA

hsa-let-7g/Upstream/4957351; hsa-mir-12124/Downstream/1120313;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/258811, chr3-CpG: 38/Downstream/106865

Upstream sequence

AGGTGGAAACCCTAAACCACAACCAAGTCCATCCATAGGGTTTTCCCCATGAAGGTTACCACAACATACTTAACATTGTTACAGACAAATTGCTGCCATT

Downstream sequence

GAAAAGCCTTTGTTTTAAAGCATGGAAAAAGCAAACAGGATGGCAAAAATAAAATAAGATGCCATAAAAGCATATGTGAATATGTTAATATATAAGATGT

Target sequence

tgacatgaagaaaaatatttagattagggggatagtggtggaggtagctagagaaggcttttctaataaggtaacatccaagaagttactttaataagtgagggagtaagacatgaggacaggagaaaagttccaggcagaaagaagagttagtgaaaatagtcctgcaataggagtgcttacatgctccaaaaacatccaagaggccaggacatgtgagtggagggaaatgagagacgagaaaatgatagattt