Basic Information
VIS ID
TVIS10020472
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1299
End
2395
Orient
+
Integrated sequence
CGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCT
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
81072047/80844922 (Hg38)
End
81073095/80845970 (Hg38)
Orient
+
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/978339; hsa-mir-10b/Downstream/4937630;
Nearest TSS
ENST00000437798/Upstream/226145; ENST00000448431/Downstream/24220;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/522249, chr2-CpG: 93/Downstream/348110
Upstream sequence
ATGCACAAGGCATGATCCTGGTGTTGTTCTGGTTTCAAGGCTGAGAGGTCGTGTGTAAGGACCTTCTGGTGCACTCCTCATGTGGCATTTCAGGGGCTCT
Downstream sequence
tgtccacggtatgtgtctcaaatcgggagatatctctactcactaagtcaactggggaccctgatggaagctctggtgtcatcaatatatggtttGTGCA
Target sequence
CAAAAGGAGATCACAGGAAACCAGGGAGGAGGCAGGGTGTGACTGACCGACTTTTTCACGTCTAATTAGGAATCAGCTCTCAATGGGGAAAATGACAGGAAAATAGATCCGAATAATTGGAAAGACATGTCTGatttataaaaaaaaaatttaaaCAGATTATTTTAAGTGGAAAAGTTTTTAAGAAAGGTCAAAGAGAGATAACCTTACCTCAGCACATTTTAAAGATAAAAGAAAGGGAGAGCTCACTTATTA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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