Basic Information
VIS ID
TVIS10020473
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1411
End
2507
Orient
+
Integrated sequence
GGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCT
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
80900700/80326565 (Hg38)
End
80901748/80327613 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1297/Upstream/2628449; hsa-mir-1267/Downstream/7291052;
Nearest TSS
ENST00000623511/Upstream/315488; ENST00000456588/Downstream/12046;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/844987, chr13-CpG: 23/Downstream/11409
Nearby gene
SPRY2(+9411) ;
Nearest cancer related gene
SPRY2(TSG, +9411) ;
Upstream sequence
gatgtaacactgagaagtgatttccttgaggatagattgccacgatggaaaggaaatgagaggttctaagaggcaggctagtggcttgtaacctacatgg
Downstream sequence
GAATATATCACCTTCTCCTCACTACTCTCTCAGCTTTCTCTGTGGCAGGTTTATTTCttttctcttttttcttttctttttcagagagggggtcttgttc
Target sequence
tttttttcaagAACGAATCCCTTTCTCATCCATGCTTGGCTGTCTGGACTCCTACCTACCACTCCATTTTTGGAAAATCATCCAAGTCCCTTTGTGACATTACCCTAAGAAACTTCCCTGATCCCACTTACTACACCCAAGATAGAGTTAGTCACTTCCCCTTCATATGTATTTTAAGTCTTTTATCATGTTTCTTATACTCTATAGTAAATACATATGTAGTTGTCCTACAGACAACTTCCAGCAAGGCAGATG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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