Basic Information
VIS ID
TVIS10020477
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1143
End
2239
Orient
+
Integrated sequence
TACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAAC
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
79114695/79818872 (Hg38)
End
79115743/79819920 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/6940209; hsa-mir-103a-1/Downstream/3020235;
Nearest TSS
ENST00000502646/Upstream/2682; ENST00000503167/Downstream/116659;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/128913, chr5-CpG: 43/Downstream/170841
Upstream sequence
ATTGATTTGGGAAGCCTTAGGAAGATTTCATAAAGGAAGGGAAATTTCTGTAACTAGGATTTCAATATTTGAAAGGAAAGGAAAAGAATGTATCCCCACT
Downstream sequence
CCTCAGTTTTCTGTTTTTGCCATGGGCTGATGGAAGTTTCTTCTGGTCTTGGGCTAGCATTTGAAAACCATGCCCTAGCTCACGTTGTTGGTGCGGAATC
Target sequence
ttatggcaggaggcaaaggaggagcaaaggcacttcttacatggtggcaggcaagagagcatgtgcaggggaattgccagttataaaaccatcagatcttgtgagacttactcactatcatgagaacagtgcaggaaaacccatccccatgattcagttacctcccaccgggtctctcccataacatgtggggattatgggagctaattctagatgaggtgagatttgagtgaggacacatccaaaccatgtcaG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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