VISDB Viral Integration Site DataBase

VIS ID

TVIS10020481

Fusion event

HBV-OSBPL3 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1469

End

2565

Orient

+

Integrated sequence

CCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT

Chromosome

chr7

Cytoband

p15.3

Reference genome

Start

End

24882009/24842390 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-4662a-5p ; hsa-mir-3151-3p ; hsa-mir-6890-3p ; hsa-mir-3163 ; hsa-mir-449b-3p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-6499-3p ; hsa-mir-539-5p ; hsa-mir-6838-5p ; hsa-mir-4519 ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-548e-5p ; hsa-mir-4712-3p ; hsa-mir-4757-3p ; hsa-mir-4517 ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-1183/Upstream/3370196; hsa-mir-10399/Downstream/1107529;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/83474, chr7-CpG: 134/Downstream/136990

Upstream sequence

aagaccagtgtggacgacacagggaggcccttgtttctacaaaaaaaaaaaaaaattttttttttaaattagttgggtgtcgtggcacatgcctgtagtc

Downstream sequence

CGGTTTTCATCTCTGGAGTTTTCCTATTTGAAGAACAAAACCAAAAATGTATACATTTAAAAACATTCTCAAGAGAAAGAAAATAAATGATTTAGTTGTA

Target sequence

CCATGATTAAAAAATATACGGGATGCTAATTTCCTTCTCTATAGTAGACACATTATTAAATAGGTAGAAGTCAAAACTATTAACCTGTACTTGAAAAGAAGTATagcactttgagaggctgaggcggatggatcacttgaggctaggagttcgaggtcagcctggccaacatgcggaagcccatctctactaaaaatacaaaaattggctgggcatggggcgcacgcctgtattcccagatacttgggaggctga