Basic Information
VIS ID
TVIS10020483
Fusion event
HBV-chr21 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1142
End
2238
Orient
+
Integrated sequence
TTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAA
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
11129578/10381830 (Hg38)
End
11130626/10382878 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10396a/Upstream/1394165; hsa-let-7c/Downstream/3023506;
Nearest TSS
ENST00000624081/Upstream/39093; ENST00000612957/Downstream/138675;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/262890, chr21-CpG: 27/Downstream/22598
Upstream sequence
caggcatcacccaccgtgGTGGCCTTTTTTTTTTTTTTTTTTAGAACAGTCCATTTGTCCTTGGAAAGCTGCATATATATTTGTATATAATAATTTGGAA
Downstream sequence
TTGCTGAGCAGAGAGGCCCAGATTTTTCCAATGTGACTTGGGGCAAATTAACCTGGCTGGTCAGCTCAAGAGACAGAGATTAAGCCGCACTACAGCCAGG
Target sequence
TTTGatttatttatttatttattttttgaggcaaaatctctctcttgtcacccaggctggagtacagtggtgtgatctcccgcctcccaggttcaagcgattctcctgcctcggtctcctgagtagGaggtttgttacatgggaatattgtctgatgttcgggtttggggtacaagtgatcccctcaccctgatactgagcatagtaaccaggaggttgccctgccctgccctgccttgcctttcttttcttttt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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